Building a multistate model from electronic health records data for modeling long-term diabetes complications.

ABSTRACT:

Objective

The progression of long-term diabetes complications has led to a decreased quality of life. Our objective was to evaluate the adverse outcomes associated with diabetes based on a patient's clinical profile by utilizing a multistate modeling approach.

Methods

This was a retrospective study of diabetes patients seen in primary care practices from 2013 to 2017. We implemented a five-state model to examine the progression of patients transitioning from one complication to having multiple complications. Our model incorporated high dimensional covariates from multisource data to investigate the possible effects of different types of factors that are associated with the progression of diabetes.

Results

The cohort consisted of 10,596 patients diagnosed with diabetes

SUBMITTER: Li RC 

PROVIDER: S-EPMC11428072 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature