Effectiveness of Short-Acting Opioid Escalation vs Initiation of a Long-Acting Opioid in Nursing Home Residents.

ABSTRACT:

Objectives

Modifications to opioid regimens for persistent pain are typically made after an initial period of short-acting opioid (SAO) use. Regimen changes may include an escalation of the SAO dosage or an initiation of a long-acting opioid (LAO) as a switch or add-on therapy. This study evaluates the comparative effectiveness between these alternative regimens in nursing home residents.

Design

A retrospective observational cohort analysis of US long-stay nursing home residents.

Setting and participants

Nursing home resident data were obtained from the national Minimum Dataset (MDS) version 3.0 and linked Medicare data, 2011-2016.

Methods

Opioid regimen changes were identified using Part D dispensing claims to identify dosage escalation of SAOs, initiation of

SUBMITTER: Nunes AP 

PROVIDER: S-EPMC11428099 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature