Bioinformatics analysis of ferroptosis in frozen shoulder.

ABSTRACT:

Objectives

Frozen shoulder is a common shoulder disease that significantly affects the patient's life and work. Ferroptosis is a new type of programmed cell death, which is involved in many diseases. However, there have been no studies reporting the relationship between frozen shoulders and ferroptosis. This study identified potential molecular markers of ferroptosis in frozen shoulders to provide more effective strategies for the treatment of frozen shoulders.

Methods

GSE238053 was downloaded from the Gene Expression Omnibus (GEO) dataset and intersected with ferroptosis genes to obtain differentially expressed genes (DEGs). The signaling pathways and biological functions of DEGs were performed by WebGestalt and Metascape. The interactions related to these DEGs and the key

SUBMITTER: Zhang H 

PROVIDER: S-EPMC11428309 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature