HIV infection increases the risk of inflammatory bowel disease: a systematic review and meta-analysis.

ABSTRACT:

Objective

In order to synthesize available results regarding human immunodeficiency virus (HIV) infection and inflammatory bowel disease (IBD), we conducted a systematic review and meta-analysis to provide quantitative estimates of associated risk.

Methods

A systematic search of four scientific databases, PubMed, the Cochrane Library, EMBASE, and Scopus, was performed. The overall odds ratio (OR) with the corresponding 95% CI was calculated via a random effects model. Sensitivity analyses and tests for publication bias were then performed.

Results

Of the 3046 articles retrieved, seven studies with a cumulative sample size greater than 57,000,000 were included in our analysis. A subsequent meta-analysis based on a random effects model (heterogeneity test, I²

SUBMITTER: Huang W 

PROVIDER: S-EPMC11428435 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature