Propensity-matched study on locally advanced esophageal cancer: surgery versus post-operative radiotherapy.

ABSTRACT:

Background

This study aims to delineate the long-term outcomes and recurrence patterns of locally advanced thoracic esophageal squamous cell carcinoma (TESCC) patients managed with or without postoperative radiotherapy (PORT).

Methods

A retrospective cohort from two academic centers, encompassing patients who initially underwent esophagectomy and were pathologically staged T3-4, was analyzed. Survival outcomes were constructed using Kaplan-Meier method, with survival significance was evaluated using the log-rank test. Propensity score matching (PSM) was utilized to balance potential selection bias.

Results

Among the 506 patients, 251 underwent surgery alone and 255 received radiotherapy following radical surgery. With a median follow-up of 49.1 months, PORT significan

SUBMITTER: Zeng Y 

PROVIDER: S-EPMC11428459 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature