Single-cell sequencing suggests a conserved function of Hedgehog-signalling in spider eye development.

ABSTRACT:

Background

Spiders evolved different types of eyes, a pair of primary eyes that are usually forward pointing, and three pairs of secondary eyes that are typically situated more posterior and lateral on the spider's head. The best understanding of arthropod eye development comes from the vinegar fly Drosophila melanogaster, the main arthropod model organism, that also evolved different types of eyes, the larval eyes and the ocelli and compound eyes of the imago. The gene regulatory networks that underlie eye development in this species are well investigated revealing a conserved core network, but also show several differences between the different types of eyes. Recent candidate gene approaches identified a number of conserved genes in arthropod eye development, but also revealed cr

SUBMITTER: Medina-Jimenez BI 

PROVIDER: S-EPMC11428483 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature