Evaluating the Physiologic Effects of Alfaxalone, Dexmedetomidine, and Midazolam Combinations in Common Blue-Tongued Skinks (Tiliqua scincoides).

ABSTRACT: Common blue-tongued skinks (Tiliqua scincoides) are popular pet reptiles; however, there has been limited research to investigate sedatives for this species. The purpose of this study was to measure the physiologic effects of four combinations of alfaxalone, dexmedetomidine, and midazolam for minor procedures such as intubation and blood collection. Eleven common blue-tongued skinks (Tiliqua scincoides) were used for this prospective, randomized cross-over study. The subcutaneous combinations were used as follows: 20 mg/kg alfaxalone (A); 10 mg/kg alfaxalone and 1 mg/kg midazolam (AM); 0.1 mg/kg dexmedetomidine and 1 mg/kg midazolam (DM); and 5 mg/kg alfaxalone, 0.05 mg/kg dexmedetomidine, and 0.5 mg/kg midazolam (ADM). Heart rate, respiratory rate, palpebral reflex, righting

SUBMITTER: Rhim H 

PROVIDER: S-EPMC11429061 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature