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Iron Trace Elements Concentration in PM10 and Alzheimer's Disease in Lima, Peru: Ecological Study.


ABSTRACT: Alzheimer's disease (AD) has been linked to air pollution, especially particulate matter (PM). PM comprises various elements, including iron-rich particles that may reach the brain through inhalation. Lima, Peru is one of the most polluted cities in Latin America, with a high rate of AD. The study aims to evaluate the association between iron (Fe) trace elements in PM10 and AD cases in Lima, Peru. This retrospective ecological study used monthly Fe concentration data from the Peruvian Ministry of Health. AD cases (ICD-10-G30) and dementia in AD cases (DAD, ICD-10-F00) were obtained from the Peruvian CDC. Fe trace element data were available for six districts in Lima for the years 2017-2019 and 2022. Cases were standardized based on ≥60-year-old populations of each district. Hier

SUBMITTER: Fano-Sizgorich D 

PROVIDER: S-EPMC11429173 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature