Association of obesity severity and duration with incidence of chronic kidney disease.

ABSTRACT:

Introduction

Obesity is a known risk factor for chronic kidney disease (CKD), but the impact of obesity severity and duration on CKD incidence is unclear.

Methods

Cumulative Excess Weight (CEW) and Cumulative Excess Waist Circumference (CEWC) scores were calculated, which represent the accumulation of deviations from expected body mass index and waist circumference values over time until the development of CKD or the end of the follow-up period. Time-dependent Cox models were used to investigate the sex-stratified association of CEW and CEWC with CKD incidence while controlling for confounding variables.

Results

Out of the 8697 participants who were evaluated in this study, 56% (4865) were women and the mean age was 40 ± 14. During the 15-year follow-up period, 41.7%

SUBMITTER: Ghazy F 

PROVIDER: S-EPMC11429187 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature