Presentation and characteristics of children with screen-detected type 1 diabetes: learnings from the ELSA general population pediatric screening study.

ABSTRACT:

Introduction

We describe the identification and management of general population screen-detected type 1 diabetes (T1D) and share learnings for best practice.

Research design and methods

Children diagnosed with T1D through a general population screening initiative, the EarLy Surveillance for Autoimmune diabetes (ELSA) study, were reviewed and described.Parents provided written, informed consent for inclusion in the case series.

Results

14 children with insulin requiring (stage 3) T1D are described. These cases offer unique insights into the features of screen-detected T1D. T1D is identified sooner through screening programs, characterized by absent/short symptom duration, median presenting glycated hemoglobin 6.6% (49 mmol/mol) and insulin requirements<0.5 units/kg/day

SUBMITTER: Quinn LM 

PROVIDER: S-EPMC11429353 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature