Bidirectional and Cross-Hemispheric Modulations of Face-Selective Neural Activity Induced by Electrical Stimulation within the Human Cortical Face Network.

ABSTRACT: A major scientific objective of cognitive neuroscience is to define cortico-cortical functional connections supporting cognitive functions. Here, we use an original approach combining frequency-tagging and direct electrical stimulation (DES) to test for bidirectional and cross-hemispheric category-specific modulations within the human cortical face network. A unique patient bilaterally implanted with depth electrodes in multiple face-selective cortical regions of the ventral occipito-temporal cortex (VOTC) was shown 70 s sequences of variable natural object images at a 6 Hz rate, objectively identifying deviant face-selective neural activity at 1.2 Hz (i.e., every five images). Concurrent electrical stimulation was separately applied for 10 seconds on four independently defined face-select

SUBMITTER: Angelini L 

PROVIDER: S-EPMC11429542 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature