Varying recombination landscapes between individuals are driven by polymorphic transposable elements.

ABSTRACT: Meiotic recombination is a prominent force shaping genome evolution, and understanding the causes for varying recombination landscapes within and between species has remained a central, though challenging, question. Recombination rates are widely observed to negatively associate with the abundance of transposable elements (TEs), selfish genetic elements that move between genomic locations. While such associations are usually interpreted as recombination influencing the efficacy of selection at removing TEs, accumulating findings suggest that TEs could instead be the cause rather than the consequence. To test this prediction, we formally investigated the influence of polymorphic, putatively active TEs on recombination rates. We developed and benchmarked a novel approach that uses PacBio lon

SUBMITTER: Huang Y 

PROVIDER: S-EPMC11429682 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature