The prevalence of Hemophilia A in males in Africa: evidence from a systematic review and meta-analysis.

ABSTRACT:

Background

Hemophilia A (HA) is an X-linked recessive bleeding disorder characterized by reduced or absent coagulation factor (F) VIII activity. The empirical evidence on the prevalence of HA in Africa has reported inconsistent findings and seems to present such a wide range of prevalence that it is hard to swiftly ascertain its average extent. Hence, this review aimed to pool the results of primary studies reporting the prevalence of HA into a single estimate in the region.

Methods

We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Articles published in EMBASE, PubMed, Web of Science, SCOPUS, Science Direct, and Cochrane Library databases were searched. Observational studies revealing the prevalence of HA in Africa betwee

SUBMITTER: Debela MB 

PROVIDER: S-EPMC11430118 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature