Oligometastatic Urothelial Cancer and Stereotactic Body Radiotherapy: A Systematic Review and an Updated Insight of Current Evidence and Future Directions.

ABSTRACT:

Background

Stereotactic body radiation therapy (SBRT) is the most commonly used metastasis-directed therapy (MDT) for oligometastatic urothelial carcinoma (omUC). Despite efforts in defining this disease entity, open questions remain concerning the role of MDT and the use of biomarkers, imaging, and its combination with systemic therapies. The aim of the present systematic review is to provide an updated overview of the current clinical evidence on SBRT for omUC in terms of survival and local control benefits. We also aim to provide updates on controversial areas and future directions in this emerging field.

Methods

With a systematic approach, following PRISMA recommendations, we searched two databases to identify and select articles published up until March 2024 reporting t

SUBMITTER: Angrisani A 

PROVIDER: S-EPMC11430162 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature