Mammalian Inner Ear-Resident Immune Cells-A Scoping Review.

ABSTRACT:

Background

Several studies have demonstrated the presence of resident immune cells in the healthy inner ear.

Aim

This scoping review aimed to systematize this knowledge by collecting the data on resident immune cells in the inner ear of different species under steady-state conditions.

Methods

The databases PubMed, MEDLINE (Ovid), CINAHL (EBSCO), and LIVIVO were used to identify articles. Systematic reviews, experimental studies, and clinical data in English and German were included without time limitations.

Results

The search yielded 49 eligible articles published between 1979 and 2022. Resident immune cells, including macrophages, lymphocytes, leukocytes, and mast cells, have been observed in various mammalian inner ear structures under steady-state conditions

SUBMITTER: Karayay B 

PROVIDER: S-EPMC11430779 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature