Exploring Hydrogel Nanoparticle Systems for Enhanced Ocular Drug Delivery.

ABSTRACT: Drug delivery to the ocular system is affected by anatomical factors like the corneal epithelium, blinking reflex, aqueous blood barrier, and retinal blood barrier, which lead to quick removal from the site and inefficient drug delivery. Developing a drug delivery mechanism that targets specific eye tissue is a major hurdle for researchers. Our study examines the challenges of drug absorption in these pathways. Hydrogels have been researched as a suitable delivery method to overcome some obstacles. These are developed alone or in conjunction with other technologies, such as nanoparticles. Many polymer hydrogel nanoparticle systems utilizing both natural and synthetic polymers have been created and investigated; each has pros and cons. The complex release mechanism of encapsulated agents fr

SUBMITTER: Arabpour Z 

PROVIDER: S-EPMC11430953 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature