Hepatic Transcriptome Reveals Potential Key Genes Contributing to Differential Milk Production.

ABSTRACT:

Background

Despite the widespread adoption of TMR or PMR and the formulas designed to sufficiently cover the cows' requirements, individual dairy cows' milk production varies significantly. The liver is one of the most important organs in cow lactation metabolism and plays an essential role in the initiation of lactation.

Objectives

This study aimed to investigate the potential key genes in the liver contributing to the different milk production.

Methods

We enrolled 64 cows and assigned them to high or low milk yield (MY) groups according to their first 3 weeks of milk production. We performed RNAseq for 35 liver samples with 18 from prepartum and 17 from postpartum cows.

Results

The continuous milk yield observation showed a persistently higher milk yield in h

SUBMITTER: Du C 

PROVIDER: S-EPMC11431119 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature