The Diagnostic Potential of Non-Invasive Tools for Oral Cancer and Precancer: A Systematic Review.

ABSTRACT:

Objectives

This systematic review aimed to analyse the published evidence for the use of non-invasive methods for the early detection of oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMDs).

Methods

The literature was systematically searched through several databases: PubMed, Cochrane Library, and Web of Science. Additional exploration was performed through cross-checks on the bibliographies of selected reviews. The inclusion criteria involved studies assessing the application of non-invasive tests on humans in the screening, diagnosis, or surveillance of OSCC or OPMDs and reporting sensitivity (SE) and specificity (SP). The Newcastle-Ottawa scale (NOS) was applied to assess the quality of the studies included.

Results

The search strate

SUBMITTER: Pierfelice TV 

PROVIDER: S-EPMC11431589 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature