Dataset Information

Manufacture and Initial Characterisation of RAPID^TM Biodynamic Haematogel, an Autologous Platelet and Leukocyte-Rich Plasma Gel for Diabetic Foot Ulcers.

ABSTRACT: This observational study reports the process for the manufacture of RAPID^TM Biodynamic Haematogel and explores the properties of the platelet and leukocyte-rich plasma gels formed. Gels were manufactured from 60 mL of human blood using the protocol of Biotherapy Services. Platelet and leukocyte content, time-to-gel, gel weight and the temporal profile of liquid exudation from the gels were measured, along with the content of growth factors VEGF and PDGF in the releasate. The effect of the releasate on human keratinocyte (HaCat) cell proliferation was also determined. The platelet and leukocyte concentrations in donor blood were 1.60-8.10 × 10⁸ and 1.00 × 10⁶-2.00 × 10⁷ cells/mL, which were concentrated 2.67- and 1.12-fold, respectively, during pr

SUBMITTER: Olszewska A

PROVIDER: S-EPMC11431608 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature

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Dataset Information

Manufacture and Initial Characterisation of RAPID^TM Biodynamic Haematogel, an Autologous Platelet and Leukocyte-Rich Plasma Gel for Diabetic Foot Ulcers.

OmicsDI is part of the ELIXIR infrastructure

Tweets

Dataset Information

Manufacture and Initial Characterisation of RAPIDTM Biodynamic Haematogel, an Autologous Platelet and Leukocyte-Rich Plasma Gel for Diabetic Foot Ulcers.

OmicsDI is part of the ELIXIR infrastructure

Tweets

Manufacture and Initial Characterisation of RAPID^TM Biodynamic Haematogel, an Autologous Platelet and Leukocyte-Rich Plasma Gel for Diabetic Foot Ulcers.