Every Third Male Patient with Acromegaly Recovers from Hypogonadism after Neurosurgical Treatment.

ABSTRACT: Background: Acromegaly is a rare endocrine condition caused by excessive growth hormone (GH) production. Hypogonadotropic hypogonadism (HH) affects 30%-50% of acromegaly patients. Objectives: This study examined the frequency of HH in men with acromegaly and the effects of neurosurgical treatment during the follow-up period. Materials and Methods: A retrospective analysis of medical records from January 2015 to December 2022 was conducted. Data included clinical history, laboratory results, and pituitary MRI findings. Statistical analysis was performed using Statistica 13.3. Results: Patients were divided into two groups: a cross-sectional sample (preoperative n = 62; postoperative n = 60) and a longitudinal sample (n = 53). In the longitudinal sample, preoperat

SUBMITTER: Derwich-Rudowicz A 

PROVIDER: S-EPMC11432164 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature