Daily Brain Metabolic Rhythms of Wild Nocturnal Bats.

ABSTRACT: Circadian rhythms are found in a wide range of organisms and have garnered significant research interest in the field of chronobiology. Under normal circadian function, metabolic regulation is temporally coordinated across tissues and behaviors within a 24 h period. Metabolites, as the closest molecular regulation to physiological phenotype, have dynamic patterns and their relationship with circadian regulation remains to be fully elucidated. In this study, untargeted brain metabolomics was employed to investigate the daily rhythms of metabolites at four time points corresponding to four typical physiological states in Vespertilio sinensis. Key brain metabolites and associated physiological processes active at different time points were detected, with 154 metabolites identified as r

SUBMITTER: Wang T 

PROVIDER: S-EPMC11432702 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature