MALDI-TOF MS Profiling and Its Contribution to Mosquito-Borne Diseases: A Systematic Review.

ABSTRACT: Mosquito-borne diseases are responsible for hundreds of thousands of deaths per year. The identification and control of the vectors that transmit pathogens to humans are crucial for disease prevention and management. Currently, morphological classification and molecular analyses via DNA barcoding are the standard methods used for vector identification. However, these approaches have several limitations. In the last decade, matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry (MALDI-TOF MS) profiling has emerged as an innovative technology in biological sciences and is now considered as a relevant tool for the identification of pathogens and arthropods. Beyond species identification, this tool is also valuable for determining various life traits of arthropod vectors.

SUBMITTER: Costa MM 

PROVIDER: S-EPMC11432722 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature