S-(+)-Carvone, a Monoterpene with Potential Anti-Neurodegenerative Activity-In Vitro, In Vivo and Ex Vivo Studies.

ABSTRACT: Carvone, a natural monoterpene, has been identified in various plants, giving them a characteristic scent. Enantiomers (R-(-) and S-(+)) reveal specific biological activities that are successfully used in traditional medicine for their antifungal, antibacterial, antiparasitic, and anti-influenza properties. The presented paper is based on S-(+)-carvone, characterized by a specific caraway scent, which revealed rich biological activities both in vitro and in vivo. Thus, the aim of the study was to evaluate the potential anti-neurodegenerative activity of S-(+)-carvone, including in vitro experiments (butyrylcholinesterase inhibitory, neuro- and hepatotoxicity as well as neuro- and hepatoprotective activity), in vivo (memory acquisition, locomotor activity), and e

SUBMITTER: Wojtunik-Kulesza KA 

PROVIDER: S-EPMC11434264 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature