The Vaginal Microbiome: Patient- versus Physician-Collected Microbial Swab: A Pilot Study.

ABSTRACT: The composition of the vaginal microbiota prior to an IVF/IVF-ICSI treatment can predict the chance of achieving a pregnancy. To improve clinical applicability and be more patient-friendly, the self-collection of vaginal samples would be preferable. However, the reliability of patient-collected samples compared to physician-collected samples remains unclear. This study compares microbiome outcomes from patient-collected versus physician-collected vaginal samples. This is a prospective pilot study consisting of two cohorts: Cohort I involved patient self-sampling of the vagina, followed by a physician-collected vaginal swab, while Cohort II involved the reversed order of collection. The interspace profiling (IS-Pro) technique was used to analyze the microbiota composition in all samples. Fr

SUBMITTER: Gao XS 

PROVIDER: S-EPMC11434400 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature