Performance Comparison of Four Hepatitis E Antibodies Detection Methods.

ABSTRACT: HEV antibody detection constitutes the main screening test for HEV infection. The aim of this study is to compare the sensitivity and specificity of four techniques: LIAISON^® MUREX DiaSorin anti-HEV IgG and anti-HEV IgM assays, Hepatitis E VIRCLIA^® IgM and IgG monotests, WANTAI HEV-IgM and IgG ELISA and VIDAS^® anti-HEV IgM and IgG tests in five panels of samples configurated according to the immunoblot (RecomLine, Mikrogen, Neuss, Germany). Anti-HEV IgM sensitivity in the acute phase was 100% in all techniques, while sensitivity, including the immediate convalescence phase, was 96.74% for LIAISON^®, 83.14% for VIRCLIA^®, 84.78% for WANTAI and 88.04% for VIDAS^®. Anti-HEV IgM specificity was 100% for both LIAISON^® and

SUBMITTER: Munoz-Chimeno M 

PROVIDER: S-EPMC11434459 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature