Evaluation of the Impact of Infusion Set Design on the Particulate Load Induced by Vancomycin-Piperacillin/Tazobactam Incompatibility.

ABSTRACT:

Introduction

Drug incompatibilities are among the most common medication errors in intensive care units. A precipitate can form and block the catheter or cause an adverse event in the patient. Intensive care units have implemented various strategies for limiting the occurrence of these incompatibilities, which have already been studied in vitro under standardized conditions. The objective of the present in vitro study was to continue these assessments by determining the impact of the infusion line geometry and the drugs' position in the infusion set-up on the prevention of vancomycin-piperacillin/tazobactam incompatibility.

Methods

Infusion lines with a different common volume, a multilumen medical infusion device, a dilute vancomycin solution, and separate infusions of inco

SUBMITTER: Negrier L 

PROVIDER: S-EPMC11435023 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature