Automated Production of [⁶⁸Ga]Ga-Desferrioxamine B on Two Different Synthesis Platforms.

ABSTRACT: Background/Objectives: PET imaging of bacterial infection could potentially provide added benefits for patient care through non-invasive means. [⁶⁸Ga]Ga-desferrioxamine B-a radiolabelled siderophore-shows specific uptake by human-pathogenic bacteria like Staphylococcus aureus or Pseudomonas aeruginosa and sufficient serum stability for clinical application. In this report, we present data for automated production of [⁶⁸Ga]Ga-desferrioxamine B on two different cassette-based synthesis modules (Modular-Lab PharmTracer and GRP 3V) utilising commercially obtainable cassettes together with a licensed ⁶⁸Ge/⁶⁸Ga radionuclide generator. Methods: Quality control, including the determination of radiochemical purity, as well as a

SUBMITTER: Kraihammer M 

PROVIDER: S-EPMC11435116 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature