Genomics Insights into <i>Mycolicibacterium Hassiacum</i> Causing Infection in a Cat with Pyogranulomatous Dermatitis and Panniculitis.

ABSTRACT: Mycolicibacterium hassiacum (homotypic synonym: Mycobacterium hassiacum) represents an ungrouped thermotolerant rapidly growing mycobacteria (RGM) species occasionally associated with infections and disease in humans. In this report, we describe a case of pyogranulomatous dermatitis and panniculitis due to M. hassiacum in an immunocompetent adult cat. To the best of our knowledge, this represents the first report of M. hassiacum infection in animals. We also report the results of the in-depth genome characterization of the isolate using a combined short- and long-read whole-genome sequencing (WGS) approach. We observed the lack of acquired-resistance genes and no evidence of mutations in housekeeping genes associated with resistance to rifampicin and isoniazid.

SUBMITTER: Smedile D 

PROVIDER: S-EPMC11435378 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature