Safety of COVID-19 Vaccines among People with History of Allergy: A European Active Surveillance Study.

ABSTRACT: Background: Conventional vaccines rarely cause severe allergic reactions. However, the rapid development and approval of COVID-19 vaccines left limited initial data on their adverse reactions, particularly in individuals with a history of allergy. The aim of this study was to assess and compare the safety profile of different doses and brands of COVID-19 vaccines in subjects with a history of allergy vs. those without a history of allergy. Methods: From February 2021 to February 2023, a web-based prospective study gathered vaccinee-reported outcomes using electronic questionnaires across eleven European countries. Baseline and up to six follow-up questionnaires captured data on vaccinee demographics, as well as both solicited and unsolicited adverse reactions. Results:

SUBMITTER: Luxi N 

PROVIDER: S-EPMC11435548 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature