Structural properties of promoters: similarities and differences between prokaryotes and eukaryotes.

ABSTRACT: During the process of transcription, RNA polymerase can exactly locate a promoter sequence in the complex maze of a genome. Several experimental studies and computational analyses have shown that the promoter sequences apparently possess some special properties, such as unusual DNA structures and low stability, which make them distinct from the rest of the genome. But most of these studies have been carried out on a particular set of promoter sequences or on promoter sequences from similar organisms. To examine whether the promoters from a wide variety of organisms share these special properties, we have carried out an analysis of sets of promoters from bacteria, vertebrates and plants. These promoters were analyzed with respect to the prediction of three different properties, such as DNA

SUBMITTER: Kanhere A 

PROVIDER: S-EPMC1143579 | biostudies-literature | 2005

REPOSITORIES: biostudies-literature