Inflammatory Manifestations Associated With Gut Dysbiosis in Alzheimer's Disease.

ABSTRACT: Recent studies strongly suggest that gut microbiome can influence brain functions and contribute to the development of Alzheimer's disease (AD). However, reported changes in the gut microbiomes in AD patients from different countries are not similar, and more research is needed to reveal the relationships between human microbiomes and AD in diverse ethnic populations. There is also an assumption that microbiome-associated peripheral inflammation might drive the development of sporadic AD. This cross-sectional study is aimed at analyzing the gut microbial profile and exploring potential associations with blood cytokines and some clinical parameters among individuals diagnosed with Alzheimer's in Kazakhstan. Consistent with previous studies, we have found that the microbial landscape in AD r

SUBMITTER: Kozhakhmetov S 

PROVIDER: S-EPMC11436273 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature