Reproducibility of intravoxel incoherent motion quantification in the liver across field strengths and gradient hardware.

ABSTRACT:

Purpose

To evaluate reproducibility and interlobar agreement of intravoxel incoherent motion (IVIM) quantification in the liver across field strengths and MR scanners with different gradient hardware.

Methods

Cramer-Rao lower bound optimization was performed to determine optimized monopolar and motion-robust 2D (b-value and first-order motion moment [M₁]) IVIM-DWI acquisitions. Eleven healthy volunteers underwent diffusion MRI of the liver, where each optimized acquisition was obtained five times across three MRI scanners. For each data set, IVIM estimates (diffusion coefficient (D), pseudo-diffusion coefficients ( d1*$$ {d}_1^{\ast } $$ and d2*$$ {d}_2^{\ast } $$ ), blood velocity SDs (V_b1 and V_b2), and perfusion fractions [f₁ and

SUBMITTER: Simchick G 

PROVIDER: S-EPMC11436311 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature