Prenatal maternal immune activation predicts observed fearfulness in infancy.

ABSTRACT: Fear reactivity is an early emerging temperament trait that predicts longer term behavioral and health outcomes. The current analysis tests the hypothesis, an extension of prior research on maternal immune activation (MIA), that the prenatal maternal immune system is a reliable predictor of observed fear reactivity in infancy. The analysis is based on a prospective longitudinal cohort study that collected data from the first trimester and conducted observational assessments of temperament at approximately 12 months of age (n = 281 infants). MIA was assessed from immune biomarkers measured in maternal blood at each trimester; infant temperament was assessed using the Laboratory Temperament Assessment Battery assessment at 12 months; covariates included family and sociodemographic fac

SUBMITTER: Serrano J 

PROVIDER: S-EPMC11436485 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature