Impact of the transpulmonary pressure on right ventricle impairment incidence during acute respiratory distress syndrome: a pilot study in adults and children.

ABSTRACT:

Background

Right ventricle impairment (RVI) is common during acute respiratory distress syndrome (ARDS) in adults and children, possibly mediated by the level of transpulmonary pressure (P_L). We sought to investigate the impact of the level of P_L on ARDS-associated right ventricle impairment (RVI).

Methods

Adults and children (> 72 h of life) were included in this two centers prospective study if they were ventilated for a new-onset ARDS or pediatric ARDS, without spontaneous breathing and contra-indication to esophageal catheter. Serial measures of static lung, chest wall, and respiratory mechanics were coupled to critical care echocardiography (CCE) for 3 days. Mixed-effect logistic regression models tested the impact of lung stress (ΔP_L) a

SUBMITTER: Vedrenne-Cloquet M 

PROVIDER: S-EPMC11436589 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature