Comprehensive analysis of the prognostic value of pre-treatment nutritional indicators in elderly rectal cancer patients.

ABSTRACT: Nutritional status assessment has been deemed essential in treating elderly cancer patients. This study aims to investigate and compare the prognostic value and clinical utility of pre-treatment nutritional indicators in elderly rectal cancer (RC) patients. We retrospectively collected data from 361 elderly rectal cancer patients. The optimal cut-off values for pre-treatment nutritional indicators were calculated using ROC curve analysis. Univariate and multivariate Cox analyses were conducted to identify independent prognostic nutritional indicators. The predictive performance and clinical utility of these independent nutritional indicators was evaluated using time-dependent ROC. Multivariate analyses showed that body mass index (BMI), prognostic nutritional index (PNI), geriatric nutriti

SUBMITTER: Qiu J 

PROVIDER: S-EPMC11436709 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature