Effect of timing of intubation on clinical outcomes of patients with septic shock: a retrospective cohort study.

ABSTRACT: Evidence-based data regarding the timing of the application of invasive mechanical ventilation among adults with septic shock is insufficient. The guidelines fail to provide clear advice about the optimal time to initiate this support. Consequently, we aimed to investigate whether early intubation could improve survival rates in septic shock patients. We conducted a retrospective analysis of the MIMIC-IV database to evaluate the effectiveness of early intubation on mortality in a cohort of septic shock patients. Adults diagnosed with septic shock, according to the Sepsis-3 definition, were included. They were categorized into an early intubation group (first 8 h after vasopressor initiation) and a non-early intubation group (unexposed). A propensity score matching (PSM) analysis was used t

SUBMITTER: Xu J 

PROVIDER: S-EPMC11436761 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature