Reliability of the spot urine protein/creatinine ratio for assessing proteinuria in patients with renal disease.

ABSTRACT:

Objective

This study aimed to assess the reliability of the spot urine protein/creatinine (sP/Cr) ratio for evaluating proteinuria across different ranges and renal functions.

Methods

In this retrospective study, we analyzed 24-hour urine protein excretion (24 h UP) and sP/Cr measurements in 216 patients with renal disease. Pearson correlation and Bland-Altman analyses were performed to evaluate the correlation and agreement between 24 h UP and the sP/Cr.

Results

The patients were categorized into the following three 24 h UP groups: 150 to 299 mg/24 hours, 300 to 3499 mg/24 hours, and >3500 mg/24 hours. Significant positive correlations were found between the sP/Cr and the first two 24 h UP groups (r = 0.9104 and r = 0.9721, respectively) but not between the third gro

SUBMITTER: Huang F 

PROVIDER: S-EPMC11437542 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature