Characteristics and outcomes of biopsy-proven lupus nephritis in the Eastern Cape province of South Africa.

ABSTRACT:

Objective

In Africa, the treatment outcomes of lupus nephritis (LN) are not well known. This is especially true in the current era where contemporary treatment options are more widely available. This retrospective study aimed to measure the outcomes of biopsy-proven LN treated at the Livingstone Tertiary Hospital (LTH) Renal Unit in Gqeberha (formerly Port Elizabeth), South Africa and to identify predictors of a poor outcome.

Methods

A retrospective cohort study of 131 patients with biopsy-proven LN who had a kidney biopsy between 01 January 2012 to 31 December 2021 as identified from the biopsy register. A sub-analysis of 107 patients with proliferative and/or membranous LN was performed.

Results

Mean age was 31.4 ± 12.7 years with a female predominance of 86.3%. At

SUBMITTER: Gerber H 

PROVIDER: S-EPMC11437693 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature