Cerebellar tDCS combined with augmented reality treadmill for freezing of gait in Parkinson's disease: a randomized controlled trial.

ABSTRACT:

Background

Parkinson's disease (PD) is often accompanied by gait disorders and freezing of gait (FoG), disabling symptoms that are resistant to conventional dopamine treatments. Given the cerebellum's connectivity with the motor cortex and basal ganglia, and its implication in PD, combining transcranial direct current stimulation targeting the cerebellum (ctDCS) with physical exercise might improve gait and balance.

Objective

This study aimed to evaluate the effectiveness of a novel rehabilitation approach that combines noninvasive cerebellar stimulation with motor-cognitive training via an augmented reality treadmill (C-Mill VR⁺) in individuals with PD and FoG.

Methods

Seventeen individuals with PD exhibiting FoG were enrolled in a randomized controlled tr

SUBMITTER: Pisano F 

PROVIDER: S-EPMC11438075 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature