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Inflammatory and immune variables as predictors of survival in dogs with myxomatous mitral valve disease.


ABSTRACT:

Background

We aimed to investigate the association between selected inflammatory and immune variables and survival of dogs with myxomatous mitral valve disease (MMVD). We evaluated data of 62 client-owned dogs with MMVD, grouped into preclinical, stable congestive heart failure (CHF) and unstable CHF. Univariate Cox proportional hazards regression analysis was used to quantify the association of white blood cell count, concentrations and percentages of T lymphocytes and their subtypes (T helper lymphocytes, cytotoxic T lymphocytes, double positive T lymphocytes, double negative T lymphocytes) and B lymphocytes with survival. P values < 0.1 in individual groups and P values < 0.05 in the group of all patients were considered significant. Spearman correlation coefficients between sig

SUBMITTER: Cimerman M 

PROVIDER: S-EPMC11438168 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature