Association between Metabolic Syndrome and Musculoskeletal Status: A Cross-Sectional Study of NHANES.

ABSTRACT:

Objective

The metabolic effects of metabolic syndrome (MetS) on musculoskeletal metabolism are controversial. This study explored the effect of MetS on bone mineral density (BMD) and muscle quality index (MQI).

Methods

Data from the NHANES database from 2011 to 2014 were extracted, and nonpregnant participants aged 45-59 years were included. The included data were first weighted by complex sampling, and then, the effect of MetS on BMD and MQI was analyzed using multifactorial linear regression. We then performed a stratified analysis by gender and BMI classification. Moreover, a mediation analysis of MetS on BMD was conducted, with MQI as a mediating variable. A propensity score matching analysis method with a complex sampling design was additionally performed to verify the

SUBMITTER: Shi Y 

PROVIDER: S-EPMC11438510 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature