Investigating the association between the triglyceride-glucose index and peripheral artery disease: a systematic review and meta-analysis.

ABSTRACT:

Background

Peripheral artery disease (PAD) is a common disease associated with atherosclerosis, leading to significant mortality and morbidity worldwide. Our study focuses on the association between insulin resistance (IR) and PAD, specifically investigating the triglyceride-glucose index (TyG) as a potential surrogate marker of IR in the context of PAD by pooling the existing studies on this topic.

Methods

Online databases, including PubMed, Embase, Scopus, and the Web of Science, were searched to find the studies comparing the TyG index in PAD vs. control, reporting the TyG index among PAD severities, and assessing the association of increase in TyG with PAD prevalence. Random-effect meta-analysis was performed to calculate the standardized mean difference (SMD) and 95% co

SUBMITTER: Samavarchitehrani A 

PROVIDER: S-EPMC11438956 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature