Gender and contemporary risk of adverse events in atrial fibrillation.

ABSTRACT:

Background and aims

The role of gender in decision-making for oral anticoagulation in patients with atrial fibrillation (AF) remains controversial.

Methods

The population cohort study used electronic healthcare records of 16 587 749 patients from UK primary care (2005-2020). Primary (composite of all-cause mortality, ischaemic stroke, or arterial thromboembolism) and secondary outcomes were analysed using Cox hazard ratios (HR), adjusted for age, socioeconomic status, and comorbidities.

Results

78 852 patients were included with AF, aged 40-75 years, no prior stroke, and no prescription of oral anticoagulants. 28 590 (36.3%) were women, and 50 262 (63.7%) men. Median age was 65.7 years (interquartile range 58.5-70.9), with women being older and having other difference

SUBMITTER: Champsi A 

PROVIDER: S-EPMC11439109 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature