Lymph node ratio as an indicator of nodal status in the assessment of survival and recurrence in vulvar cancer: A cohort study.

ABSTRACT:

Background

Inguinal lymph node (LN) metastasis and particularly the number of metastatic lymph nodes (NMLN) represent a determinant prognostic factor in vulvar squamous cell carcinoma (VSCC). However, the NMLN may be related to the number of removed LNs. Therefore, the lymph node ratio (LNR) reflects not only the burden of LN involvement but also the quality and extent of lymphadenectomy.

Objectives

To investigate the value of the LNR and the count of LN on overall survival (OS) and recurrence-free survival (RFS).

Design

This study is a retrospective, longitudinal, institution-based study.

Methods

This study included 192 patients treated for VSCC at the Salah Azaiez Institute between 1994 and 2022. Clinical, pathological, and evolutionary data were reported. Su

SUBMITTER: Mansouri H 

PROVIDER: S-EPMC11439166 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature