The effectiveness of fibrin sealants in head and neck surgery: a systematic review and meta-analysis.

ABSTRACT:

Background

Fibrin sealants are increasingly used in head and neck surgery to aid hemostasis, but individual studies lack conclusive evidence. This systematic review investigates their effectiveness compared to placebo or usual care in head and neck surgery.

Methods

Studies comparing fibrin sealant to placebo or usual care in patients 18 years or older who have undergone soft tissue surgery of the head and neck with drain placement were included. Primary outcomes include wound complications and time to surgical drain removal postoperatively. Secondary outcomes include length of hospital stay, drain volume output, surgical management of hematoma, blood transfusion rates, and adverse reactions. Electronic databases were searched on October 2023 for randomized controlled and qua

SUBMITTER: Nguyen M 

PROVIDER: S-EPMC11439234 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature