Association of life's essential 8 with mortalities in patients with alcohol-related liver disease.

ABSTRACT:

Background

Alcohol-related liver disease (ALD) and cardiovascular diseases share some common risk factors. This study aims to investigate the associations between Life's Essential 8 (LE8), a comprehensive measure of cardiovascular health (CVH), and outcomes of ALD.

Methods

Data were obtained from the 2011-2018 National Health and Nutrition Examination Survey (NHANES). Cox proportional hazards models were employed to assess the relationships between LE8 and all-cause and cardiovascular mortality in patients with ALD. Additionally, restricted cubic splines (RCS), piecewise regression, and subgroup analyses were conducted.

Results

A total of 5321 ALD patients were included in this study with a mean LE8 score of 67.38. During a median follow-up period of 63 months, 228 al

SUBMITTER: Zhang X 

PROVIDER: S-EPMC11439271 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature