The Association between the Gut Microbiota and Erectile Dysfunction.

ABSTRACT:

Purpose

Explore the causal relationship between the gut microbiota and erectile dysfunction (ED) at phylum, class, order, family, and genus levels, and identify specific pathogenic bacteria that may be associated with the onset and progression of ED.

Materials and methods

The genetic variation data of 196 human gut microbiota incorporated in our study came from the human gut microbiome Genome Wide Association Studies (GWAS) dataset released by the MiBioGen Consortium. The GWAS statistics for ED were extracted from one study by Bovijn et al., which included 223,805 participants of European ancestry, of whom 6,175 were diagnosed with ED. Subsequently, Mendelian randomization (MR) analysis was carried out to explore whether a causal relationship exists between the gut microbiot

SUBMITTER: Zhu T 

PROVIDER: S-EPMC11439808 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature