Study of a precise treatment protocol for patients with consciousness disorders based on the brain network analysis of functional magnetic resonance imaging.

ABSTRACT:

Objective

How to conduct objective and accurate individualized assessments of patients with disorders of consciousness (DOC) and carry out precision rehabilitation treatment technology is a major rehabilitation problem that needs to be solved urgently.

Methods

In this study, a multi-layer brain network was constructed based on functional magnetic resonance imaging (fMRI) to analyze the structural and functional brain networks of patients with DOC at different levels and to find regulatory targets (imaging markers) with recovery potential for DOC. Then repeated transcranial magnetic stimulation (rTMS) was performed in DOC patients to clinically validate.

Results

The brain network connectivity of DOC patients with different consciousness states is different, and the mos

SUBMITTER: Wang P 

PROVIDER: S-EPMC11439825 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature