Point-of-care creatinine vs. central laboratory creatinine in the critically ill.

ABSTRACT:

Objective

Frequent measurement of creatinine by point-of-care testing (POCT) may facilitate the earlier detection of acute kidney injury (AKI) in critically ill patients. However, no robust data exist to confirm its equivalence to central laboratory testing. We aimed to conduct a multicenter study to compare POCT with central laboratory creatinine (CrC) measurement.

Design

Retrospective observational study, using hospital electronic medical records. Obtained paired point-of-care creatinine (CrP) from arterial blood gas machines and CrC.

Setting

Four intensive care units in Queensland, Australia.

Participants

Critically ill patients, where greater than 50% of POCT contained creatinine.

Main outcome measures

Mean difference, bias, and limits of agreement b

SUBMITTER: White KC 

PROVIDER: S-EPMC11440060 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature