SLC25A19 drives colorectal cancer progression by regulating p53.

ABSTRACT:

Background

Investigating the molecular mechanism of colorectal cancer (CRC), a common lethal malignancies worldwide, is of great clinical significance. Solute carrier family 25 member 19 (SLC25A19) is a member of the solute carrier family that contribute to cellular functions, including tumor biology. Recently, many studies have attention on uncovering the relationship of SLC25A19 with malignant cancers, but its precise involvement in the regulation of CRC has not been thoroughly understood. This study sought to uncover the role and mechanism of SLC25A19 in CRC development.

Methods

The GEPIA database and immunohistochemical staining were utilized to detect the expression of SLC25A19 in CRC tissues. The functional influences of SLC25A19 on CRC cell phenotypes were evaluated t

SUBMITTER: Jiang J 

PROVIDER: S-EPMC11440145 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature